intestinal secretion — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1244	Celiprolol hydrochloride	Selecor,Selectrol	Adrenergic Receptor
	Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.		Adrenergic Receptor
T25719	Lidamidine	Lidamidina,Lidamidinum	Others
	Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.		Others
T15005	CP-66948		Histamine Receptor
	CP-66948 is a potent histamine H2 receptor antagonist with inhibitory effect on gastric acid secretion and can be used to protect gastric and intestinal mucosa.		Histamine Receptor
TP1376	GLP-1(7-37) acetate(106612-94-6 free base)	GLP-1(7-37) acetate	Others , Glucagon Receptor
	Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.		Others , Glucagon Receptor
T3984	GLP-1(7-36), amide	MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide	Glucagon Receptor
	GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-...		Glucagon Receptor
T36126	TMP-153
	Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and choleste...
T27829	Lidamidine Hydrochloride	WHR1142A,WHR-1142A,Lidaral,WHR 1142A
	Lidamidine Hydrochloride is an alpha2-adrenergic receptor agonist. Lidamidine Hydrochloride inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.
T37892	GLP-1(7-36), amide TFA
	GLP-1(7-36), amide TFA is a prominent intestinal hormone known to stimulate glucose-induced insulin secretion from β cells[1].
TP1141	GLP-1(7-36), amide acetate	GLP-1(7-36) Acetate,Human GLP-1-(7-36)-amide Acetate
	GLP-1(7-36) Acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
T78510	Zolimidine		Others
	Zolimidine, an imidazopyridine derivative, functions as an orally active antiulcer agent. It promotes mucus secretion in intestinal mucosal cells and enhances the intestinal wall's resistance to ulceration. Studies demon...		Others
TP1976	Oxyntomodulin	Oxyntomodulin (porcine, bovine)
	GLP-1 receptor agonist. Endogenous preproglucagon-derived neuropeptide that modulates feeding and metabolism. Also secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stom...
TP1054	PACAP (1-38), human, ovine, rat TFA	Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP...
T75757	GIP, human TFA
	GIP, human TFA, a 42-amino acid peptide hormone, functions as a glucose-dependent insulin secretion stimulator and a weak gastric acid secretion inhibitor. Released from intestinal K cells following nutrient ingestion, i...
T71340	Mizagliflozin sebacate
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from...
T26868	BMS-986118	BMS 986118
	BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabete...
T81571	PACAP (1-38) free acid TFA
	PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin secretion and promoting the release of vasoactive intestinal...
T69953	MK-8666 Tris
	MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pa...
T10447	BAA473		Others
	BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial c...		Others
T70468	MK-8666
	MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancrea...
T83694	Gastric Inhibitory Peptide (1-42) (porcine) TFA	GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
	Gastric inhibitory peptide (GIP) (1-42), an endogenous incretin hormone comprising 42 amino acids, promotes insulin secretion. Expressed in the intestinal neuroendocrine K cells and submandibular gland, it enters circula...